openalexPLoS Computational Biology2026-07-23
A cost-optimized 5-protein panel revolutionizes systemic lupus erythematosus diagnosis
Wenhua Lv, Zhenwei Shang, Chen Sun, Yuping Zou, Siyu Wei, Haiyan Chen, et al.
Early diagnosis of systemic lupus erythematosus (SLE) is hindered by a lack of reliable biomarkers. This study sought to identify and evaluate diagnostic plasma protein biomarkers for SLE. We analyzed plasma protein profiles, polygenic risk scores (PRS), and clinical data from 54…