openalexFrontiers in Medicine2026-07-24
An exploratory exome-wide machine learning analysis identifies candidate host gene signatures associated with Long COVID in a large admixed Brazilian cohort
Aléxia Stefani Siqueira Zetum, Danielle Ribeiro Campos da Silva, Vinícius do Prado Ventorim, Felipe Ataides Mion, Felipe dos Santos Passarela, Henrique Perini Rosa, et al.
Introduction Genetic factors have been suggested as modifiers of vulnerability to postCOVID-19 sequelae, referred to as Long COVID (LC). We hypothesize that LC may involve central nervous system (CNS)-related mechanisms, influenced by neuroinflammatory, autoimmune, viral mechanis…