openalexFrontiers in Immunology2026-07-24
Spatial transcriptomic mapping of early immune responses to an adjuvanted recombinant hemagglutinin vaccine
Laurelle Jackson, Sarah Williams, J. Sinclair, Ana Kume, Azadeh Bahadoran, Ingeborg M. Langohr, et al.
Vaccination relies on innate and adaptive responses initiated at the injection site followed by activation in draining lymph nodes. However, high-plex, spatially resolved maps that couple injection site signals with transcriptomic programs in draining lymph nodes over time are st…