openalexFrontiers in Immunology2026-07-24
CT-guided intratumoral immunotherapy for advanced solid tumors: a prospective clinical study of safety and systemic antitumor effects
Yongqiong Ou, Jian Zhang, Hu Tan, B-C He, Tianheng Li, Manting Liu, et al.
Background Systemic administration of immunotherapy via intravenous injection is frequently associated with off-target toxicity throughout the body. In contrast, intratumoral injection has emerged as a promising strategy to mitigate systemic adverse effects. However, data regardi…