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Chengxiang Hu

3 papers indexed

crossrefInternational Journal of Molecular Sciences2025-12-12

Computational Insights into the Molecular Mechanisms of Coptis chinensis Franch. in Treating Chronic Atrophic Gastritis: An Integrated Network Pharmacology, Machine Learning, and Molecular Dynamics Study

Chengxiang Hu, Yang Liu, Yiyao Ding, Yue Jin, Weiwei Han

Chronic atrophic gastritis (CAG) is a precancerous gastric condition with limited therapeutic interventions, and the mechanisms underlying the benefits of Coptis chinensis Franch. (CCF) remain insufficiently defined. This study employed an integrated computational strategy to cla…

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crossrefInternational Journal of Molecular Sciences2025-11-21Cited by 1

Elucidating the Mechanisms of Chrysanthemum Action on Atopic Dermatitis via Network Pharmacology and Machine Learning

Shiying Li, Yongxin Jiang, Chengxiang Hu, Yiyao Ding, Xueqi Fu, Shu Xing, et al.

Chrysanthemum (Chrysanthemum morifolium Ramat.) has been recognized as both a food and medicinal substance in China since 2002 and possesses antioxidant, anti-inflammatory, antibacterial, and immunomodulatory activities. Previous studies suggest that Chrysanthemum may alleviate s…

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crossrefInternational Journal of Molecular Sciences2023-11-03Cited by 12

Network Pharmacology Combined with Machine Learning to Reveal the Action Mechanism of Licochalcone Intervention in Liver Cancer

Fangfang Guo, Xiaotang Yang, Chengxiang Hu, Wannan Li, Weiwei Han

There are reports indicating that licochalcones can inhibit the proliferation, migration, and invasion of cancer cells by promoting the expression of autophagy-related proteins, inhibiting the expression of cell cycle proteins and angiogenic factors, and regulating autophagy and…

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