arxivstat.MLcs.LGq-bio.GN2026-07-05
Causal ASCEND: Scalable Two-tier Causal Discovery on High Dimensional Multi-omics Data
Biological systems exhibit a hierarchical structure, characterised by directed flow from upstream regulators to downstream effects. Although this ordering provides a natural scaffold for causal inference, most causal discovery and GRN methods either ignore the tiered organisation…