Eric Féraille

Claudin-3 is expressed at the macula densa and is associated with altered glomerular filtration in claudin-3 knockout mice

Alexandra Chassot, Eric Féraille, Ali Sassi

Claudin-3 is a tight junction protein expressed in the distal nephron, notably in the thick ascending limb of Henle’s loop and the distal convoluted tubule, where it acts as an aldosterone-regulated paracellular barrier to sodium and chloride transport. Here, we demonstrate that…Read more