openalexFrontiers in Oncology2026-07-24
Phosphorylation of tumour suppressor Amotl2 by IKBKE kinase promotes YAP1 signalling, enhancing glioblastoma growth
Gaochao Guo, Yan Sun, Rujun Hong, Yalin Lu, Xingjie Chen, Liming Zhao, et al.
Inhibitor of nuclear factor kappa-B kinase subunit epsilon (IKBKE), a member of the serine/threonine kinase family, is an important oncogene in glioblastoma. IKBKE is involved in the progression of multiple tumours in glioblastoma (GBM), including tumour invasion, migration, and…