crossrefProcesses2026-06-18
Prediction and Interpretation of the Volumetric Mass Transfer Coefficient in Bioreactors Using a No-Code Platform for Autonomous Machine Learning Model Selection
Ho-Yeon Lee, Yonghee Shin, Jongsun Won, Jin Ho Lee, Sangmin Park, Sang-Min Paik, et al.
The volumetric mass transfer coefficient (kLa) governs the design, operation, and scale-up of aerobic bioprocesses, yet its dependence on reactor geometry, impeller design, operating conditions, and fluid properties limits prediction by empirical correlations. Machine learning (M…