Large language models (LLMs) remain expensive to fine-tune because full-parameter updates require substantial memory, compute, and per-task storage. We study whether saliency signals originally developed for pruning can be reused to choose where a model should adapt. We propose S…
Synthesis planning aiming to find pathways of reactions for a target molecule is one of the most important and challenging tasks in drug discovery. Recent progress has produced both specialized deep-learning retrosynthesis systems and general-purpose large language models, but ob…