arxivcs.LGcs.AI2026-07-21
ABOPD: Antibody CDR Design via On-Policy Distillation
Zhuo Yang, Jiaying He, Jiaqing Xie, Daolang Wang, Xipeng Qiu, Yuxin Wang, et al.
Antibodies are essential therapeutic molecules, and their complementarity-determining regions (CDRs) form the primary antigen-recognition interface. Recent protein generative models have demonstrated broad capabilities in biomolecular design, yet post-training strategies for down…