Jose K. James

Optimizing Clinical Trial Protocols Using EHR-Derived Heterogeneous Treatment Effects

Xiaodi Li, Munhuwan Lee, Pengyang Li, Xiaoke Liu, Jose K. James, Patricia A. Pellikka, et al.

Traditional randomized trials often obscure clinically meaningful heterogeneity in treatment response by focusing on average effects. Leveraging real-world data to emulate clinical trials and estimate heterogeneous treatment effects (HTEs) offers a promising path toward more prec…Read more