crossrefMachine Learning and Knowledge Extraction2026-07-22
Alzheimer’s Disease Detection Based on Machine Learning and Deep Learning Frameworks: A Cross-Dataset Comparative Performance Analysis and Assessment of Clinical Readiness
Keenan Ramnarain, Rito Clifford Maswanganyi, Philani Khumalo
Alzheimer’s disease (AD) is the most prevalent neurodegenerative disorder worldwide, affecting approximately 56.9 million people in 2021 and projected to reach 152 million by 2050. Its defining pathological features, amyloid-beta plaques and neurofibrillary tangles, accumulate fo…