crossrefGenes2025-08-29Cited by 1
Integrating Transcriptomics, Network Pharmacology, and Machine Learning to Reveal Transglutaminase 2 (TGM2) as a Key Target Mediating Taurocholate Efficacy in Colitis
Junhong Zhu, Huijin Jia, Lanlan Yi, Guangyao Song, Pengfei Fu, Wenjie Cheng, et al.
Background: Ulcerative colitis (UC) is a chronic inflammatory disease of the colon with a rising global incidence. Natural conjugated taurocholic acid (TCA) possesses anti-inflammatory properties and shows potential therapeutic effects against UC, although the underlying mechanis…