openalexScientific Reports2026-07-23
Low-density lipoprotein receptor-related protein 1 and factor VIII are independent predictors of target vessel revascularization in myocardial infarction patients receiving PCSK9 inhibitors
Cao M, Ximei Liu, Ziyi Liu, Yuanqiang Guo, Lingli Zhang, Zhuhua Yao
Low-density lipoprotein receptor-related protein 1 (LRP1) mediates the clearance of circulating factor VIII (FVIII) and contributes to vascular thrombotic homeostasis. Although prior basic studies have confirmed that proprotein convertase subtilisin/kexin type 9 inhibitors (PCSK9…