openalexScience Advances2026-07-23Cited by 7
Single-cell chromatin state transitions during epigenetic memory formation
Taihei Fujimori, Abby R. Thurm, Simon Gaudin, Carolina Rios-Martinez, Benjamin R. Doughty, Michaela M. Hinks, et al.
Repressive chromatin modifications compact chromatin and mediate heritable gene silencing, but how structural changes quantitatively relate to epigenetic memory remains unclear. Using targeted recruitment of the KRAB repressor to induce H3K9me3 at a reporter gene, combined with s…