openalexbioRxiv (Cold Spring Harbor Laboratory)2026-07-23
The ribosome-associated quality control factor Vms1 protects mitochondrial import and homeostasis during translation stress
Gülsah Göktas, Vitasta Tiku, Nikita A. Kvasov, Andrei Makhon, Michal Breker, Fabian den Brave, et al.
Mitochondrial protein synthesis and import are tightly coordinated to maintain cellular proteostasis, yet how cytosolic translation stress affects mitochondrial homeostasis remains poorly understood. Here, we investigated the cellular consequences of general translation stress us…