openalexFrontiers in Nutrition2026-07-23
Cycloastragenol improves tolerance to acute hypoxic exhaustive exercise stress in mice: integrated network pharmacology and experimental evidence
D Liu, Y Zhang, Minghui Jia, Yimeng Gu, Xuefeng Xi, Y Zhang
Background Acute hypoxic exposure combined with exhaustive exercise can impair exercise performance and induce metabolic, inflammatory, oxidative, and tissue stress. Cycloastragenol, a bioactive constituent of Astragalus membranaceus , has shown antioxidant and tissue-protective…