3 papers indexed
Dawei Li, Xiaotian Jiang, Mingyi Hong
Barzilai--Borwein (BB) method has shown strong practical performance in continuous optimization, yet its convergence dynamics remains poorly understood. In particular, a central unresolved question is whether BB converges superlinearly for almost every strictly convex quadratic p…
Ruoxi Gao, Jiangweizhi Peng, Ziqi Chen, Frazier N. Baker, David C. Kombo, John L. Kane, et al.
Drug discovery and development is time-consuming and resource-intensive, motivating computational approaches such as diffusion models for de novo drug design. Many such models follow the structure-based drug design (SBDD) paradigm, generating molecules to fit a target binding poc…
Zijian Zhang, Rizhen Hu, Athanasios Glentis, Dawei Li, Chung-Yiu Yau, Hongzhou Lin, et al.
Reinforcement learning (RL) has become a central component of post-training large language models (LLMs), yet little is understood about how RL adaptation is distributed across transformer layers. Existing approaches typically update all model parameters uniformly, implicitly ass…