openalexFrontiers in Aging Neuroscience2026-07-24
AI-enabled multimodal neuroimaging for neurotransmitter mapping in normal aging and age-related disease
Paige Hewitt, H.D. Kim, Thomas A. Vida
Aging reshapes neurotransmitter systems through nonlinear and region-specific shifts that alter excitatory–inhibitory balance, weaken metabolic coupling, and destabilize large-scale neural networks. PET, MRS, molecular MRI, and optical imaging quantify elements of these trajector…