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Sebastian Ziegelmayer

2 papers indexed

arxivcs.CVcs.AIcs.CLcs.LG2026-07-22

Self-supervision drives representational convergence in medical foundation models more than clinical supervision

Soroosh Tayebi Arasteh, Sebastian Ziegelmayer, Mahshad Lotfinia, Lisa Adams, Sven Nebelung, Jakob Nikolas Kather, et al.

Medical image encoders from different groups are increasingly treated as interchangeable, on the assumption that scale and clinical supervision concentrate their representations onto a shared structure. Whether this convergence is real, what produces it, and whether it is clinica…

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arxivcs.AIcs.CL2026-07-11

Information-seeking failures of large language models in agentic clinical reasoning

Krischan Braitsch, Laura K. Schmalbrock, Theresa Weltermann, Andrew F. Berdel, Isabella Miller, Kai Tran, et al.

Large language models achieve high scores on medical knowledge assessments, yet clinical reasoning requires actively deciding what to investigate under uncertainty. We developed an agentic evaluation framework in hematologic oncology in which models must proactively request clini…

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