Sebastiano Cultrera di Montesano

Score Distributions, Not Cells: Evaluating Single-Cell Perturbations Under Class Overlap

Youssef Marrakchi, Davide D'Ascenzo, Sebastiano Cultrera di Montesano

Most classification problems assume the classes are roughly separable, so that an individual sample can usually be assigned to one class. Single-cell perturbation data violates this assumption: two perturbations can produce different populations of cells while overlapping so much…Read more