openalexFrontiers in Cardiovascular Medicine2026-07-23
Mixed short-chain fatty acids and high-fiber diet reshape SCFA profiles and attenuate post-infarction cardiac fibrosis in mice
Zhiyuan Xu, Qi Zhong, Shunrong Zhao, 赵凯迪, Junhua Zhang
Background Short-chain fatty acids (SCFAs) are microbiota-derived metabolites implicated in immunometabolic regulation. How their systemic and myocardial signatures diverge during post-infarction remodeling, and how these signatures relate to cardiac fibrosis, remains poorly char…