Violeta Basten-Romero

Two-Stage Fine-Tuning for Protein Sequence Generation with Targeted Amino-Acid Composition

Violeta Basten-Romero, Rubén Muñoz-Tafalla, Anna María Díaz-Rovira, Bertran Miquel-Oliver, Isaac Filella-Merce, Víctor Guallar

Protein language models are standard priors for biological sequence generation, but steering them toward explicit distributional design targets remains largely unexplored. We study a constrained protein generation problem in which sequences must match a desired amino-acid (AA) co…Read more