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Wei Chen

8 papers indexed

openalexFrontiers in Neuroscience2026-07-24

Identification and validation of mitophagy and astrocyte-related molecular signature in the pathogenesis of Alzheimer's disease: evidence from ensemble learning-driven multi-omics and clinical validation

Jun Liu, Wei Chen

Background Alzheimer's disease (AD) is a progressive neurodegenerative disorder with limited diagnostic tools and therapeutic options. Dysregulated mitophagy in astrocytes plays a pivotal role in AD pathogenesis. This study aims to identify a mitophagy and astrocyte (MA)-associat…

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openalexFrontiers in Medicine2026-07-24

Construction and validation of a machine learning-based model for predicting pneumonia risk in patients with hemorrhagic stroke

Darong Lu, Wanting Shi, Wenhua Li, Luo Yefangxin, Y X Li, Qiong Qin, et al.

Objective This study aimed to develop and validate a distinct, stable, and interpretable predictive model using machine learning techniques to identify individuals at high risk of pneumonia early after admission. The goal was to provide a potential quantitative reference for impl…

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arxivcs.LGcs.AImath.ST2026-07-20

A Continual Validation, Updating, and Decision-Making Framework for Self-Adaptive Digital Twins via Robust Model Predictive Control: A Case Study in Additive Manufacturing

Yi-Ping Chen, Ying-Kuan Tsai, Vispi Karkaria, Seul Lee, Daniel Apley, Wei Chen

Digital Twins rely on surrogate models to mirror physical systems in real time, yet these models can degrade as operating conditions evolve, a phenomenon known as concept drift. Maintaining surrogate fidelity under drift, particularly when models must also capture aleatoric uncer…

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arxivcs.LGcs.CL2026-07-12

From Self-Attention to Connection Laplacian: A Unified Operator View of Transformers

Binbin Lin, Wei Chen, Yalun Li, Wenxiao Wang, Jieping Ye, Xiaofei He

Self-attention is a ubiquitous primitive in modern sequence models, yet its operator-level geometry is only partially understood. We view a token sequence as a vector field over the token-position graph and identify attention as a connection walk: messages are aggregated by a non…

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arxivcs.GRcs.CV2026-07-09

HoloTetSphere: Unified TetSphere Mesh Reconstruction for Physical Simulations

YaQiao Dai, Renjiao Yi, Zhirui Gao, Wei Chen, Kai Xu, Chenyang Zhu

Standard pipelines for physics-ready 3D reconstruction rely on a decoupled two-stage paradigm: extracting surface geometry followed by an error-prone tetrahedralization process. While recent Lagrangian methods like TetSphere Splatting attempt to bypass this by directly optimizing…

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arxivcs.HCcs.AI2026-07-07

VisTCP: A Visualization Framework to Construct Knowledge-Graph-Based Representation for Traditional Chinese Painting

Zhiguang Zhou, Fengling Zheng, Miaoxin Hu, Lina You, Jin Wen, Huan Liu, et al.

Structured representation can characterize semantic objects and relationships in images. It provides a possible effective way for the semantic understanding of Traditional Chinese Paintings (TCPs) to better support archaeology and art history research. However, most image-oriente…

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arxivcs.CV2026-06-25

SpatialFlow-GRPO: Where Spatial Credit Drives Image Editing

Yankai Yang, Yancheng Long, Wei Chen, Xingyu Lu, Hongyang Wei, Bin Wen, et al.

Recent online reinforcement learning has substantially improved image editing quality. However, existing Flow-GRPO-style methods usually rely on a single whole-image reward, which makes fine-grained editing optimization difficult. We observe that a key obstacle in image editing i…

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