openalexmedRxiv2026-07-23
Precision Management of Fludrocortisone-Related Hypertension Risk in Congenital Adrenal Hyperplasia: A Machine Learning Approach to Personalized Dosing
Shengkai Du, Z Y Chen, Gaohui Zhu, Li T, Weiting Deng, Wenqing Ji, et al.
Congenital adrenal hyperplasia (CAH) is a rare inherited disorder requiring lifelong hormone replacement therapy. Excessive hormone replacement poses a significant risk for long-term complications, such as hypertension; however, quantitative approaches for optimizing dosing remai…