openalexFigshare2026-07-26
Integrated multi-level transcriptomic and bioinformatics analysis identifies lipid metabolism–ubiquitination signatures and reveals ATG5, ASB4, LDLR, and CD36 as Candidate biomarkers in insulin resistance
Jicui Chen, G H Wu, Wei Shi, Xianjun Ma
Insulin resistance (IR) is the core pathological basis of type 2 diabetes mellitus (T2DM). This study aimed to identify core lipid metabolism-ubiquitination-related feature genes in IR. Integrative transcriptomic and functional analysis screened differential genes via multiple ma…