Xu Steven Xu

Iron homeostasis landscape informs patient survival and neoadjuvant chemotherapy response in cancer

Xiaoqing Fan, Kangna Cao, Xu Steven Xu, Xiaoyu Yan

Abstract Background Cancer cells frequently alter iron metabolism by increasing uptake or decreasing export, promoting oncogenesis and proliferation. However, the quantitative relationship between iron homeostasis and cancer remains underexplored. Methods and results We simplifie…Read more

Multitask learning of longitudinal circulating biomarkers and clinical outcomes: identification of optimal machine-learning and deep-learning models

Min Yuan, Shixin Su, Haolun Ding, Yaning Yang, Manish Gupta, Xu Steven Xu