openalexFrontiers in Oncology2026-07-24
Down-regulation of THBS2 inhibits the malignant progression of Burkitt lymphoma by blocking the PI3K/AKT/c-MYC pathway
Yan Xu, Shengquan Liu, Shaoxiong Wang, Y Huang
Background Thrombospondin 2 (THBS2) is overexpressed in various solid tumors and is a prognostic gene of Burkitt lymphoma (BL), but its role and molecular mechanism in BL still need to be explored. Methods Western blot (WB) detected the protein expression of THBS2 in BL cells. si…