Y U N F E N Yan

FetalADM: a double-layer ensemble model based on SMOTE_KM and RF-RFE for fetal trisomy 21, 18, and 13 detections

Xia Sun, Jianjiang Zhu, Xuequn Mao, Y U N F E N Yan, Limei Xu, Wen Zeng, et al.

Abstract Noninvasive prenatal testing (NIPT), which utilizes high-throughput sequencing technology to analyze cell-free DNA fragments from maternal peripheral plasma, has been widely adopted in clinical practice. However, accurately detecting fetal trisomy remains a challenge. To…Read more