openalexFrontiers in Bioengineering and Biotechnology2026-07-23
Multiphysics finite element analysis of vertebral stability in simulated osteolytic lumbar defects treated with 125I brachytherapy and vertebroplasty
Lulu Du, J Zhang, Jinhong Zhou, Yanbo Hu, Qiyu Sun, Jiaqi Yin, et al.
Objective This study evaluates the impact of radiation dose, thermal effects, and mechanical factors on vertebral stability and safety in a finite element model of simulated osteolytic defects and compared 125 I seed brachytherapy alone with 125 I brachytherapy combined with perc…