arxivcs.CV2026-07-06
DriftST: One-Step Generative Inference of Spatial Transcriptomics from H\&E Histology
Yuhang Yang, Yonggan Bu, Shengyuan Zhou, Yiming Luo, Kai Zhang
Spatial Transcriptomics (ST) measures gene expression while preserving spatial context, but its high cost and low throughput leave public datasets small. Inferring expression directly from widely available Hematoxylin and Eosin (H&E) stained histology offers a cost-effective alte…