openalexFrontiers in Endocrinology2026-07-23
Acupuncture modulates extracellular vesicle-miRNA-HMOX1 axis to inhibit ferroptosis in polycystic ovary syndrome: integrating machine learning, in vitro and in vivo studies
X W Wu, Yuanyin Li, Na Wang, S J Guo, H Chen, T H Chen, et al.
Background Acupuncture therapy shows promise for polycystic ovary syndrome (PCOS), but its molecular mechanisms remain unclear. This study investigates whether acupuncture alleviates PCOS by regulating granulosa cell (GC) ferroptosis via extracellular vesicles (EVs). Methods Bioi…