openalexFrontiers in Immunology2026-07-23
Post-transcriptional regulation via alternative polyadenylation and piRNA shapes macrophage responses in psoriasis
Benfan Lin, Xiwang Du, Leihong Lu, Z Wang, Yuanzhang Zhao, Yue Feng, et al.
Background Post-transcriptional regulatory mechanisms underlying autoimmune diseases remain poorly understood. Here, we employed integrated multi-omics approaches to systematically dissect the role of alternative polyadenylation (APA) and piRNA-mediated regulation in psoriasis pa…