arxivcs.LGcs.AIcs.CEq-bio.QM2026-07-07
AbICL: In-Context Learning for Antigen-Specific Antibody Affinity Ranking
Zhiyuan Chen, Jing Hu, Junzhe Wang, Yueyang Huang, Xinyi Yang, Zhaoyang Wang, et al.
Accurate ranking of antibody candidates according to their binding affinity is essential for therapeutic antibody discovery. However, existing methods treat affinity comparisons independently and ignore the contextual information encoded in other labeled comparisons, limiting the…