openalexFrontiers in Endocrinology2026-07-24
Machine learning and bioinformatics identify and validate membrane protein biomarkers for type 2 diabetes mellitus
Tong Liu, Zhaoyuan Tang, Zulipikaer Aierken, Jie Zhang, Cheng Lei
Introduction Type 2 diabetes mellitus (T2DM) is among the most rapidly increasing metabolic disorders worldwide. Membrane proteins, integral components of biological membranes, are pivotal in insulin signal transduction and significantly contribute to the pathogenesis of T2DM. Ho…