openalexbioRxiv (Cold Spring Harbor Laboratory)2026-07-24
Machine Learning-Assisted Evolution of Broadly Functional Enzyme Libraries
Ravi Lal, Jason Yang, Ziyan Zhang, Frances H. Arnold
Biocatalysis offers sustainable solutions to pressing challenges in chemical synthesis by exploiting the remarkable efficiency and selectivity of enzymes. Importantly, enzymes are able to accommodate non-native substrates and mediate transformations outside of their natural reper…