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crossrefInternational Journal of Molecular Sciences2025-11-28Cited by 1

Special Issue “Raman Spectroscopy and Machine Learning in Human Disease”

Ivan Bratchenko

Nowadays, modern optical techniques offer a variety of approaches for the analysis of tissues and biofluids [...]

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crossrefInternational Journal of Molecular Sciences2024-09-11Cited by 5

Renal Cell Carcinoma Discrimination through Attenuated Total Reflection Fourier Transform Infrared Spectroscopy of Dried Human Urine and Machine Learning Techniques

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Renal cell carcinoma (RCC) is the sixth most common cancer in men and is often asymptomatic, leading to incidental detection in advanced disease stages that are associated with aggressive histology and poorer outcomes. Various cancer biomarkers are found in urine samples from pat…

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crossrefInternational Journal of Molecular Sciences2026-07-05

Machine Learning and Deep Learning Frameworks for Human–Virus Protein–Protein Interaction Prediction: Emerging Architectures, Methods, Benchmarks, and Challenges

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The outbreak of coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has emerged as one of the most significant global health crises in recent history. Coronaviruses are a diverse group of RNA viruses classified into alpha,…

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crossrefInternational Journal of Molecular Sciences2025-02-27Cited by 5

Therapeutic Mechanisms of Medicine Food Homology Plants in Alzheimer’s Disease: Insights from Network Pharmacology, Machine Learning, and Molecular Docking

Shuran Wen, Ye Han, You Li, Dongling Zhan

Alzheimer’s disease (AD) is a progressive neurodegenerative disorder characterized by a gradual decline in cognitive function. Currently, there are no effective treatments for this condition. Medicine food homology plants have gained increasing attention as potential natural trea…

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crossrefInternational Journal of Molecular Sciences2025-03-08Cited by 3

Comparison of Deep Learning and Traditional Machine Learning Models for Predicting Mild Cognitive Impairment Using Plasma Proteomic Biomarkers

Kesheng Wang, Donald A. Adjeroh, Wei Fang, Suzy M. Walter, Danqing Xiao, Ubolrat Piamjariyakul, et al.

Mild cognitive impairment (MCI) is a clinical condition characterized by a decline in cognitive ability and progression of cognitive impairment. It is often considered a transitional stage between normal aging and Alzheimer’s disease (AD). This study aimed to compare deep learnin…

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crossrefInternational Journal of Molecular Sciences2024-09-24Cited by 2

PROTA: A Robust Tool for Protamine Prediction Using a Hybrid Approach of Machine Learning and Deep Learning

Jorge G. Farias, Lisandra Herrera-Belén, Luis Jimenez, Jorge F. Beltrán

Protamines play a critical role in DNA compaction and stabilization in sperm cells, significantly influencing male fertility and various biotechnological applications. Traditionally, identifying these proteins is a challenging and time-consuming process due to their species-speci…

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