Machine learning (ML) and bioinformatics are catalyzing a new era in biomedical research, enabling unprecedented insights into the complex systems that govern human health and disease [...]
Nowadays, modern optical techniques offer a variety of approaches for the analysis of tissues and biofluids [...]
Subhadeep Basu, Dipanwita Adhikary, Kuntal Ghosh, Swarup Chattopadhyay, Shramana Deb, Ritwick Mondal, et al.
The outbreak of coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has emerged as one of the most significant global health crises in recent history. Coronaviruses are a diverse group of RNA viruses classified into alpha,…
Bogdan Adrian Buhas, Lucia Ana-Maria Muntean, Guillaume Ploussard, Bogdan Ovidiu Feciche, Iulia Andras, Valentin Toma, et al.
Renal cell carcinoma (RCC) is the sixth most common cancer in men and is often asymptomatic, leading to incidental detection in advanced disease stages that are associated with aggressive histology and poorer outcomes. Various cancer biomarkers are found in urine samples from pat…
Frank Emmert-Streib, Olli Yli-Harja
The idea of a digital twin has recently gained widespread attention. While, so far, it has been used predominantly for problems in engineering and manufacturing, it is believed that a digital twin also holds great promise for applications in medicine and health. However, a proble…
Shuran Wen, Ye Han, You Li, Dongling Zhan
Alzheimer’s disease (AD) is a progressive neurodegenerative disorder characterized by a gradual decline in cognitive function. Currently, there are no effective treatments for this condition. Medicine food homology plants have gained increasing attention as potential natural trea…
Jingbo Cao, Ziyao Yang, Qi Zhang, Siwei Zou, Huning Zhang, Anning Yang, et al.
This study integrates multidimensional computational approaches—network toxicology, machine learning, molecular docking, and molecular dynamics simulation—to systematically elucidate the toxic mechanism by which the environmental pollutant diisononyl cyclohexane-1,2-dicarboxylate…