openalexScience Advances2026-07-24
Interpretable dynamic quantitative vascular morphometry features using SHAP for anti-angiogenic therapy response prediction
Kui Hu, Qian Cai, Jia Xu, Shuangquan Ai, Wuling Ou, Liu Y
Anti-angiogenic therapy benefits vary, with response rates of 40 to 70%, highlighting the need for early biomarkers to identify responders. We developed an automated machine learning framework that uses delta quantitative vascular morphometry features from standard contrast-enhan…