openalexFrontiers in Immunology2026-07-24
Platelets in systemic lupus erythematosus: from hemostatic allies to pathogenic drivers
Yanzuo Wu, Ze Yang, Shuo Huang, Jie Bao, Yongsheng Fan, Guanqun Xie
Systemic lupus erythematosus (SLE) is a multisystem autoimmune disease; hematologic involvement is common and strongly associated with prognosis. Platelets—the second most abundant cellular component of peripheral blood—are anucleate cytoplasmic fragments. Their canonical roles i…