crossrefAdvanced Science2026-05-14
A Bioinspired Three‐Dimensional High‐Curvature Nano‐Interface Integrated Microfluidic Chip for Small Extracellular Vesicles Enrichment and Machine Learning‐Assisted Prostate Cancer Precision Diagnosis
Le Wang, Yizhong Liang, Manan Sulaiman, Jiaqi Du, Ming Jiang, Zhihua Wang, et al.
ABSTRACT The efficient and unbiased isolation of small extracellular vesicles (sEVs) from complex biological fluids remains a major obstacle for clinical diagnostics. Here, we report a bioinspired microfluidic chip that integrates a three‐dimensional high‐curvature TiO 2 nano‐int…