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crossrefAI2023-12-01Cited by 28

Evaluating the Performance of Automated Machine Learning (AutoML) Tools for Heart Disease Diagnosis and Prediction

Lauren M. Paladino, Alexander Hughes, Alexander Perera, Oguzhan Topsakal, Tahir Cetin Akinci

Globally, over 17 million people annually die from cardiovascular diseases, with heart disease being the leading cause of mortality in the United States. The ever-increasing volume of data related to heart disease opens up possibilities for employing machine learning (ML) techniques in diagnosing and predicting heart conditions. While applying ML demands a certain level of computer science expertise—often a barrier for healthcare professionals—automated machine learning (AutoML) tools significantly lower this barrier. They enable users to construct the most effective ML models without in-depth technical knowledge. Despite their potential, there has been a lack of research comparing the performance of different AutoML tools on heart disease data. Addressing this gap, our study evaluates three AutoML tools—PyCaret, AutoGluon, and AutoKeras—against three datasets (Cleveland, Hungarian, and a combined dataset). To evaluate the efficacy of AutoML against conventional machine learning methodologies, we crafted ten machine learning models using the standard practices of exploratory data analysis (EDA), data cleansing, feature engineering, and others, utilizing the sklearn library. Our toolkit included an array of models—logistic regression, support vector machines, decision trees, random forest, and various ensemble models. Employing 5-fold cross-validation, these traditionally developed models demonstrated accuracy rates spanning from 55% to 60%. This performance is markedly inferior to that of AutoML tools, indicating the latter’s superior capability in generating predictive models. Among AutoML tools, AutoGluon emerged as the superior tool, consistently achieving accuracy rates between 78% and 86% across the datasets. PyCaret’s performance varied, with accuracy rates from 65% to 83%, indicating a dependency on the nature of the dataset. AutoKeras showed the most fluctuation in performance, with accuracies ranging from 54% to 83%. Our findings suggest that AutoML tools can simplify the generation of robust ML models that potentially surpass those crafted through traditional ML methodologies. However, we must also consider the limitations of AutoML tools and explore strategies to overcome them. The successful deployment of high-performance ML models designed via AutoML could revolutionize the treatment and prevention of heart disease globally, significantly impacting patient care.

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crossrefAI2024-09-24Cited by 31

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crossrefAI2025-01-21Cited by 6

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crossrefAI2024-11-14

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As machine learning (ML) transforms industries, the need for efficient model development tools using high-performance computing (HPC) and ensuring interpretability is crucial. This paper presents SIBILA, an AutoML approach designed for HPC environments, focusing on the interpreta…

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crossrefAI2026-01-21Cited by 1

Integrating Machine-Learning Methods with Importance–Performance Maps to Evaluate Drivers for the Acceptance of New Vaccines: Application to AstraZeneca COVID-19 Vaccine

Jorge de Andrés-Sánchez, Mar Souto-Romero, Mario Arias-Oliva

Background: The acceptance of new vaccines under uncertainty—such as during the COVID-19 pandemic—poses a major public health challenge because efficacy and safety information is still evolving. Methods: We propose an integrative analytical framework that combines a theory-based…

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crossrefAI2026-05-09

Machine Learning Models for Predicting Post-Hepatectomy Liver Failure: A Systematic Review

Calin Muntean, Vasile Gaborean, Razvan Constantin Vonica, Sebastian Aurelian Stefaniga, Alaviana Monique Faur, Catalin Vladut Ionut Feier

Background and Objectives: Post-hepatectomy liver failure (PHLF) remains the leading cause of mortality following hepatic resection, with reported incidence rates ranging from 1.2% to 32%. Traditional scoring systems such as the Child–Pugh score, Model for End-Stage Liver Disease…

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crossrefAI2026-01-16

A Radiomics-Based Machine Learning Model for Predicting Pneumonitis During Durvalumab Treatment in Locally Advanced NSCLC

Takeshi Masuda, Daisuke Kawahara, Wakako Daido, Nobuki Imano, Naoko Matsumoto, Kosuke Hamai, et al.

Introduction: Pneumonitis represents one of the clinically significant adverse events observed in patients with non-small-cell lung cancer (NSCLC) who receive durvalumab as consolidation therapy after chemoradiotherapy (CRT). Although clinical factors such as radiation dose (e.g.…

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