Mobile on-device AI (MoAI) systems that integrate locally deployed AI models with conventional mobile software components are emerging as a key paradigm for delivering intelligent functionality directly on end-user devices. By moving inference from remote cloud services to the local mobile environment, such systems enable privacy-preserving, low-latency, and offline-capable AI functionality, yet introduce new security risks arising from the local storage of AI models. This paper presents the first comprehensive systematization of knowledge on MoAI security, covering security pillars, attack landscape, and defense landscape of MoAI systems. We further identify unresolved gaps in current attack and defense research and point to promising directions for future research in this emerging area. Our work establishes the first systematic framework for understanding the attack and defense landscapes of MoAI systems, serving as a foundation for building secure MoAI systems and advancing research in this critical domain. Companion resources are available at https://github.com/Jinxhy/Awesome-MoAI-Security.
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